Constitutive activation of egfr is associated with tumor

HIGHLIGHTS

• who: Top from the 4505, France have published the article: Constitutive activation of EGFR is associated with tumor, in the Journal: (JOURNAL)
• what: The authors showed that EGFR is constitutively active in chondrosarcoma tumors of high-grade, whereas it is not active in low-grade tumors, suggesting that EGFR activation may be involved in chondrosarcoma tumor progression and therefore could be used as a biomarker to monitor the progression of chondrosarcoma tumors.
• how: The results showed that inhibition of EGFR produced a cell cycle arrest at G0/G1 phase and induced apoptosis of . . .
  

   

  

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