Posterior association networks and functional modules inferred from rich phenotypes of gene perturbations

HIGHLIGHTS

• who: Xin Wang and collaborators from the Cancer Research UK Cambridge Research Institute, Cambridge, Cambridgeshire, United Kingdom, Department of Oncology, University of Cambridge, Cambridge have published the paper: Posterior Association Networks and Functional Modules Inferred from Rich Phenotypes of Gene Perturbations, in the Journal: (JOURNAL) of June/28,/2012
• what: The authors report a novel experimental and computational framework to efficiently address this challenge by limiting the ‘search space' for important genetic interactions. The authors propose to integrate rich phenotypes of multiple single gene perturbations to robustly predict functional modules which can subsequently be subjected . . .
  

   

  

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