Additional sex combs-like 2 is required for polycomb repressive complex 2 binding at select targets

HIGHLIGHTS

  • who: Hsiao-Lei, Lai and Q. Tian, Wang from the Department of Biological Sciences, University of Illinois at Chicago, Chicago, Illinois, United States of America have published the research: Additional Sex Combs-Like 2 Is Required for Polycomb Repressive Complex 2 Binding at Select Targets, in the Journal: PLOS ONE | www.plosone.org of March/27,/2013
  • what: The authors show that the Asxl2-deficient heart is defective in converting H3K27me2 to H3K27me3 and in removing ubiquitin from mono-ubiquitinated histone H2A. The authors explore the molecular basis by which ASXL2 mediates gene repression in . . .

     

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