Apoe4: an emerging therapeutic target for alzheimer’s disease

HIGHLIGHTS

  • who: Mirna Safieh from the (UNIVERSITY) have published the article: ApoE4: an emerging therapeutic target for Alzheimer’s disease, in the Journal: (JOURNAL)
  • what: The second part of the review focuses on recent apoE4-targeted (from the APOE gene to the apoE protein and its interactors) therapeutic approaches that have been developed in animal models and are ready to be translated to human. This assertion and other mechanistic studies, such as the role of interaction of apoE4 with Aβ, phosphorylation of tau protein, disruption of metachondrial function, and others discussed in this review, have been . . .

     

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