HIGHLIGHTS
- who: Lavona Casson and colleagues from the Division of Hematology and Oncology, Department of Medicine, James Graham Brown Cancer Center, University of Louisville, Louisville, Kentucky, United States of have published the article: Inhibition of Ceramide Metabolism Sensitizes Human Leukemia Cells to Inhibition of BCL2-Like Proteins, in the Journal: PLOS ONE | www.plosone.org of January/16,/2013
- what: As further support that elevated ceramide and sphingosine are likely important in increasing ABT-263 induced apoptosis, the authors demonstrate that the combining ABT-263 with the sphingosine kinase inhibitor SKi-II also significantly increases ceramide . . .
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