The inhibition of polo kinase by matrimony maintains g2 arrest in the meiotic cell cycle

HIGHLIGHTS

  • who: PLoS BIOLOGY and colleagues from the Stowers Institute, University have published the article: The Inhibition of Polo Kinase by Matrimony Maintains G2 Arrest in the Meiotic Cell Cycle, in the Journal: (JOURNAL) of 28/Nov/2006
  • what: The authors show here that the Mtrm protein prevents precocious NEB. The authors demonstrate that this yeast two-hybrid finding reflects a true physical interaction in_vivo by both coimmunoprecipitation studies and by multidimensional protein identification technology (MudPIT) mass spectrometry experiments, which indicate that Mtrm binds to Polo with an approximate stoichiometry of 1:1. The authors show . . .

     

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