HIGHLIGHTS
- who: Gunadi from the (UNIVERSITY) have published the research work: Aberrant UBR4 expressions in Hirschsprung disease patients, in the Journal: (JOURNAL)
- what: The study demonstrates that expression of UBR4 is decreased in both aganglionic and ganglionic colon of HSCR patients.
- future: Future studies are necessary to further confirm the role of UBR4 in the pathogenesis of HSCR by checking the decreased of UBR4 protein expressions using western blot or immunohistochemistry and screening the pathogenic variant in the UBR4 gene using sequencing in HSCR patients. Analysis using controls without any bowel motility problem is . . .
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