Effects of mipomersen, an apolipoprotein b100 antisense, on lipoprotein (a) metabolism in healthy subjects

HIGHLIGHTS

  • who: Renu Nandakumar from the Columbia University have published the research: Effects of mipomersen, an apolipoprotein B100 antisense, on lipoprotein (a) metabolism in healthy subjects, in the Journal: (JOURNAL)
  • what: The safety data for this study have been published .
  • how: The authors examined the metabolism of Lp(a) in 14 volunteers who completed the parent study of the effects of mipomersen on apoB metabolism. The evolocumab study was conducted with subjects in a fasting state whereas the authors conducted the study with a constant steady-state supply of nutrients. Much larger studies with . . .

     

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