Síntese de complexos de platina com derivados n-benzilados de 1,3 propanodiamina, potenciais agentes antineoplásicos

HIGHLIGHTS

  • who: Mauro from the Departamento Química, Universidade Federal Juiz Fora, Juiz Fora-MG, Brazil have published the Article: SÍNTESE DE COMPLEXOS DE PLATINA COM DERIVADOS N-BENZILADOS DE 1,3 PROPANODIAMINA, POTENCIAIS AGENTES ANTINEOPLÁSICOS, in the Journal: (JOURNAL)
  • what: The authors report the preparation and characterization of analogous complexes having N-benzyl 1,3-propanediamine derivatives as ligands.

SUMMARY

    The discovery of the anticancer activity of the coordination compound cisdiaminedichloroplatinum(II) (cisplatin), and its successful clinical use, represents important progress for inorganic medicinal chemistry. Cisplatin has been approved . . .

     

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