HIGHLIGHTS
- who: Chong Zhang from the First Hospital Peking University have published the research work: Mapping the spreading routes of lymphatic metastases in human colorectal cancer, in the Journal: NATURE COMMUNICATIONS NATURE COMMUNICATIONS
- what: The authors seek to systematically investigate the lymphatic metastasis routes in CRC. Next, the authors focused on patients with liver metastases (LMs) (Fig 4b, Supplementary Figs 6-8). As observed in this study and previous reports8-10,44, different regions from the primary tumor and matched primary-metastasis pairs showed a variable extent of intratumor heterogeneity; therefore, sequencing only one region of . . .
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