ﺎﯾﺮﺘﻜﺒﻟ ةواﺮﻀﻟا ﻞﻣاﻮﻋ ﺾﻌﺑ ﺪﯾﺪﺤﺗ pasteurella multocida اﻧاﻮﯿﺤﻟاو نﺎﺴﻧﻹا تﺎﺑﺎﺻإ ﻦﻣ ﺔﻟوﺰﻌﻤﻟتﺎﺔﯿﻠﻘﺤﻟا

HIGHLIGHTS

• who: (‫ﻣﺠﻠﺔ ﻣﺮﻛﺰ ﺑﺤﻮث اﻟﺘﻘﻨﯿﺎت and colleagues from the College of Science Al-Mustansiriyah University have published the paper: ﺎﯾﺮﺘﻜﺒﻟ ةواﺮﻀﻟا ﻞﻣاﻮﻋ ﺾﻌﺑ ﺪﯾﺪﺤﺗ Pasteurella multocida اﻧاﻮﯿﺤﻟاو نﺎﺴﻧﻹا تﺎﺑﺎﺻإ ﻦﻣ ﺔﻟوﺰﻌﻤﻟتﺎﺔﯿﻠﻘﺤﻟا, in the Journal: (JOURNAL)

SUMMARY

[1‬اﻣﺎ اﻻﺻﺎﺑﺔ ﻓﻲ اﻟﺨﻨﺎزﯾﺮ ﻓﺘﻜﻮن ﺷﺪﯾﺪة وﯾﻨﺠﻢ ﻋﻨﮭﺎ ﺣﺎﻟﺔ اﻟﺘﮭﺎب اﻻﻧﻒ اﻟﻀﺎﻣﺮ ]‪ ‪. [3‬‬ ‫اﻟﻰ ﺟﺎﻧﺐ اﻻﺻﺎﺑﺎت ﻓﻲ اﻟﺤﯿﻮاﻧﺎت ﻓﺄﻧﮫ ﻣﻦ اﻟﻤﻤﻜﻦ اﻧﺘﻘﺎل اﻟﺒﻜﺘﺮﯾﺎ اﻟﻰ اﻹﻧﺴﺎن اذ ﻋﺰﻟﺖ ﻓﻲ ﺣﺎﻻت اﻟﺘﮭﺎب‬ ‫اﻟﻘﺼﺒﺎت اﻟﮭﻮاﺋﯿﺔ اﻟﺤﺎدة وﻟﺴﺎن اﻟﻤﺰﻣﺎر]‪ ‪ ،[5‬واﻟﺘﮭﺎﺑﺎت اﻟﻤﺠﺎري اﻟﺒﻮﻟﯿﺔ ]‪. [7‬ھﻨﺎﻟﻚ ﺗﻘﺎرﯾﺮ‬ ‫ﺳﻨﻮﯾﺔ ﻣﻦ ﻣﺨﺘﻠﻒ اﻧﺤﺎء اﻟﻌﺎﻟﻢ ﻋﻦ ﻋﺰل ھﺬه اﻟﺒﻜﺘﺮﯾﺎ ﻣﻦ ﻋﻀﺎت اﻟﻜﻼب واﻟﻘﻄﻂ واﻟﻤﻀﺎﻋﻔﺎت اﻟﻨﺎﺟﻤﺔ ﻋﻨﮭﺎ ]‪[8‬‬ ‫‪.‬ﯾﺴﮭﻞ اﻻﺻﺎﺑﺔ ﺑﺒﻜﺘﺮﯾﺎ ‪P. multocida‬ﻻﻣﺘﻼﻛﮭﺎ ﻟﻌﺪد ﻣﻦ ﻋﻮاﻣﻞ اﻟﻀﺮاوة ﻛﺄﻓﺮازھﺎ ﻟﻸﻧﺰﯾﻤﺎت واﻟﺬﯾﻔﺎﻧﺎت‬ ‫ﻓﻀﻼ ﻋﻦ اﻣﺘﻼﻛﮭﺎ ﻟﻠﺒﻼزﻣﯿﺪات اﻟﻤﺴﺆوﻟﺔ ﻋﻦ ﻣﻘﺎوﻣﺔ ﻋﺪد ﻣﻦ اﻟﻤﻀﺎدات اﻟﺤﯿﻮﯾﺔ ]‪. Pasteurella multocida carter A‬‬ ‫اﻟﺘﺤﺮي ﻋﻦ ﺑﻌﺾ ﻋﻮاﻣﻞ ﺿﺮاوة اﻟﺒﻜﺘﺮﯾﺎ‬ ‫اﻧﺘﺎج اﻻﻧﺰﯾﻢ اﻟﻤﺤﻠﻞ ﻟﻠﺪھﻮن ‪:Lipase‬أﺗﺒﻌﺖ ﻃﺮﯾﻘﺘﺎ اﻻﻃﺒﺎق )‪ (plate method‬واﻟﻄﺮﯾﻘﺔ اﻟﻤﺤﻮرة اﻟﺘﻲ‬ ‫اﺟﺮﯾﺖ اﯾﻀﺎ ﻓﻲ اﻻﻃﺒﺎق وﻟﻜﻦ ﺑﻌﺪ اﺿﺎﻓﺔ اﻟﻜﺎﺷﻒ اﻻﺣﻤﺮ اﻟﻤﺘﻌﺎدل ]‪ [ 12‬وذﻟﻚ ﻟﻠﺘﺤﺮي ﻋﻦ اﻧﺘﺎج اﻧﺰﯾﻢ‬ ‫‪ Lipase‬ﺑﻮﺟﻮد اﻟﻤﺎدة اﻻﺳﺎس ‪. Erythromycin (15g),‬‬ ‫‪Gentamicin (10g), Kanamycin (30g) Chloramphenicol (30g), Clindamycin‬‬ ‫‪(10g), Neomycin (10g), Novobiocin, penicillin G (30g), Tetracycline (30g).‬‬ ‫‪Lincomycin (2g). [5‬ﻟﻘﺪ اﺷﺎرت ﺑﻌﺾ اﻟﻤﺼﺎدر اﻟﻰ ﺗﻔﻮق ﺑﻜﺘﺮﯾﺎ ‪ P. multocida‬ﻋﻠﻰ ﺑﻜﺘﺮﯾﺎ‬ ‫‪ Streptococcus Pneumonia‬اﻟﻤﺴﺒﺒﺔ ﻟﺬات اﻟﺮﺋﺔ ﻣﻦ ﺣﯿﺚ ﺿﺮاوﺗﮭﺎ ﻟﻠﻔﺌﺮان اﻟﻤﺨﺘﺒﺮﯾﺔ ﻓﺎﻟﻔﺌﺮان اﻟﻤﺤﻘﻮﻧﺔ‬ ‫ورﯾﺪﯾﺎً ﺑﺎﻟﻨﻮع اﻻول ﺗﺼﻞ ﻟﻠﻜﺒﺪ واﻟﻄﺤﺎل واﻟﺮﺋﺔ واﻟﺘﺠﻮﯾﻒ اﻟﺒﺮﯾﺘﻮﻧﻲ ﺧﻼل ﻓﺘﺮة ﺳﺮﯾﻌﺔ ﻣﺴﺒﺒﺔ ھﻼك اﻟﺤﯿﻮان‬ ‫ﺧﻼل ) ‪ (12 9-‬ﺳﺎﻋﺔ اﻣﺎ اذا ﺣﻘﻨﺖ ﻋﻦ ﻃﺮﯾﻖ اﻟﺒﺮﯾﺘﻮن ﻓﺎﻧﮭﺎ ﺗﺒﺪأ ﺑﺎﻟﺘﻜﺎﺛﺮ ﺑﻌﺪ ‪ 15‬دﻗﯿﻘﺔ ﻣﻦ اﻟﺤﻘﻦ وﺗﺴﺒﺐ ﻗﺘﻞ‬ ‫ﺳﺮﯾﻊ ﻟﮭﺎ ]‪. [7‬وﻓﻖ اﻟﻨﺘﺎﺋﺞ اﻟﺴﺎﺑﻘﺔ ﯾﻤﻜﻦ اﻟﻘﻮل ان ﺿﺮاوة اﻟﻌﺰﻻت اﻟﺘﻲ ﻣﺼﺪرھﺎ اﻻﻧﺴﺎن واﻟﺤﯿﻮاﻧﺎت ﻣﺘﻘﺎرﺑﺔ ‪ ،‬ﻏﯿﺮ ان‬ ‫‪20‬‬ ‫ﻣﺠﻠﺔ ﻣﺮﻛﺰ ﺑﺤﻮث اﻟﺘﻘﻨﯿﺎت اﻻﺣﯿﺎﺋﯿﺔ )ﻋﺪد ﺧﺎص(‬ ‫اﻟﻤﺠﻠﺪ اﻟﺨﺎﻣﺲ‪ -‬اﻟﻌﺪد اﻟﺜﺎﻟﺚ‬ ‫ﻋﺰﻻت ﻛﻮﻟﯿﺮا اﻟﺪﺟﺎج ﻛﺎﻧﺖ ﺿﺎرﯾﺔ اﻛﺜﺮ ﻧﻮﻋﻤﺎ ‪.‬ﻓﯿﻤﺎ ﯾﺨﺺ ﻧﺘﺎﺋﺞ اﺳﺘﺠﺎﺑﺔ اﻟﻌﺰﻻت ﻗﯿﺪ اﻟﺪراﺳﺔ ﻟﺒﻌﺾ‬ ‫اﻟﻤﻀﺎدات اﻟﺤﯿﻮﯾﺔ ﻓﻘﺪ ﺗﺒﯿﻦ ان ﻣﺪى ﺣﺴﺎﺳﯿﺔ ھﺬه اﻟﻌﺰﻻت ﻛﺎﻧﺖ ﻣﺘﺒﺎﯾﻨﺔ ﺟﺪول )‪. @@

ACRONYMS

• PMT: Multocida toxin

LAY DEFINITIONS

• Virulence factors . . .
  

   

  

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