Molecular insights into determinants of translational readthrough and implications for nonsense suppression approaches

HIGHLIGHTS

  • who: Silvia Lombardi et al. from the (UNIVERSITY) have published the research work: Molecular Insights into Determinants of Translational Readthrough and Implications for Nonsense Suppression Approaches, in the Journal: (JOURNAL)
  • what: The authors focus on the mechanisms driving translation in normal and aberrant conditions the potential fates of mRNA in the presence of a PTC as well as on the results obtained in the research of efficient readthrough-inducing compounds. This work provided the first evidence that the favorable localization of PTCs in regions that are removed during protein processing would drive the production of . . .

     

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