HIGHLIGHTS
- who: Frame Management from the of Molecular Genetics, Institute for Liver Research, Kansai Medical University, and, Japan have published the research: J. Exp. Med. uf6d9, in the Journal: (JOURNAL) of January/21,/2002
- what: The authors first characterized BCR signaling of DT40 B cells deficient in Vav3. The authors show that phosphatidylinositol-3,4,5-trisphosphate (PIP3) generation and subsequent Akt activation are attenuated by loss of Vav3 or by introduction of dominant negative Rac1. The activity in the presence of GST/GTP S was used to normalize individual activities in each experiment. Although this . . .
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