Ck1/runx2 axis in the bone marrow microenvironment: a novel therapeutic target in multiple myeloma

HIGHLIGHTS

  • who: Anna Fregnani and collaborators from the Hematology and Clinical Immunology Branch, Department of Medicine, University of Padova, Padova, Italy have published the article: CK1/RUNX2 Axis in the Bone Marrow Microenvironment: A Novel Therapeutic Target in Multiple Myeloma, in the Journal: Cancers 2022, 14, 4173. of /2022/
  • what: The authors investigated the role of CK1α in the osteoblastogenic potential of mesenchymal stromal cells (MSCs) and its involvement in MM-MSC cross-talk.

SUMMARY

    Multiple myeloma (MM) is an incurable hematological malignancy of terminally differentiated plasma cells (PCs) which accounts for . . .

     

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