HIGHLIGHTS
- who: Giarita Ferraro and collaborators from the Department of Chemical Sciences, University of Naples Federico II, Napoli, Italy have published the research: Reaction with Proteins of a Five-Coordinate Platinum(II) Compound, in the Journal: (JOURNAL)
- what: The experiments show that complex I can react with proteins, leading to different products.
- how: Interestingly ESI MS data also reveal that when the five-coordinate compound is incubated with the two model proteins different results are obtained.
SUMMARY
Cisplatin (cis-diamminedichloridoplatinum(II)) and its second-generation analogues are among the most . . .
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