Nucleolin antagonist triggers autophagic cell death in human

HIGHLIGHTS

  • who: Top from the Department of Life, Health and Environmental Sciences, University of L'Aquila, L'Aquila, Italy have published the research: Nucleolin antagonist triggers autophagic cell death in human, in the Journal: (JOURNAL)
  • what: The authors investigated targeting NCL as a new therapeutic strategy for the treatment of this pathology. By monitoring autophagy markers such as p62 and LC3II the authors demonstrate that autophagy is enhanced after N6L treatment. On the basis of these results, NCL represents a potential tool for targeted therapy for gliomas, and thus in this work the effects of N6L . . .

     

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