3-o-sulfated heparan sulfate interactors target synaptic adhesion molecules from neonatal mouse brain and inhibit neural activity and synaptogenesis in vitro

HIGHLIGHTS

• who: Auriane Maïza from the CNRS Radboud University have published the paper: 3-O-sulfated heparan sulfate interactors target synaptic adhesion molecules from neonatal mouse brain and inhibit neural activity and synaptogenesis in vitro, in the Journal: Scientific Reports Scientific Reports of 22/02/2020
• what: The aim of the study was to characterize some signaling components and functions associated to 3S-HSs in relation to neuronal development.
• how: For this the authors used a pull-down assay approach (see Supplementary file) using biotinylated peptides and allowing to precipitate membrane receptors together . . .
  

   

  

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