Cholesterol and sphingomyelin are critical for fcγ receptor-mediated phagocytosis of cryptococcus neoformans by macrophages

HIGHLIGHTS

  • who: Arielle M. Bryan from the (UNIVERSITY) have published the paper: Cholesterol and sphingomyelin are critical for Fcγ receptor-mediated phagocytosis of Cryptococcus neoformans by macrophages, in the Journal: (JOURNAL)
  • how: Repletion with coprostanol ablated both the presence of detectable ordered nanodomains and the GPMV thermal stability (Fig 4B and Table S1 raw unnormalized F/F0 values for FRET data are shown in Fig S3B). The authors utilized various methods of lipid alteration to probe for the role of lipid rafts in phagocytosis of C. neoformans.

SUMMARY

    Since lipid rafts (high . . .

     

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