HIGHLIGHTS
- who: Aubin Fleiss et al. from the France, Université de Strasbourg, CNRS, GMGM UMR7156, Strasbourg, France Editor:, University College Dublin have published the Article: Reshuffling yeast chromosomes with CRISPR/Cas9, in the Journal: (JOURNAL) of August/29,/2019
- what: The authors report a novel application of the CRISPR/Cas9 technology allowing to generate with high efficiency both uniquely targeted and multiple concomitant reciprocal translocations in the yeast genome.
- how: The authors chose to target these five Ty3 LTRs because inducing DSB at these locations should allow significant genome reshuffling without compromising to much . . .
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