HIGHLIGHTS
- who: Delia Damp#x02019 and Avola from the (UNIVERSITY) have published the Article: High-density single cell mRNA sequencing to characterize circulating tumor cells in hepatocellular carcinoma, in the Journal: (JOURNAL) of 16/04/2018
- what: The authors provide the proof-of-principle to further develop single-cell_sequencing for biomarker development in HCC.
- how: As a proxy for expression differences in individual CTCs versus non tumoral cells and given the limitations for differential expression testing in individual samples (dropout and lack of replicates to estimate variance) the authors used the residuals of expression . . .
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