Suppression of interferon (ifn)-inducible genes and ifn-mediated functional responses in bcr-abl-expressing cells*

HIGHLIGHTS

  • who: Efstratios Katsoulidis from the c-Abl (cellular Abelson murine leukemia virus oncoprotein) were obtained from Cell Signaling Technology (Danvers, MA)Anti-Stat, was purchased from Santa Cruz Biotechnology, Inc. (Santa Cruz, CA), and anti-p-Stat, was purchased from BioVision Inc. (Mountain View, CA). U OS cells were grown in McCoy's medium supplemented with, % (v/v) fetal bovine serum and gentamycin. , cells were grown in RPMI medium supplemented with, % (v/v) fetal bovine serum and gentamycin. BA/, pSR␣ mock cells, BA/, MIGR1, and the BCR-ABL kinase-inactive BA/, MIG , KI cells were grown in . . .

     

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