HIGHLIGHTS
- who: Rebecca A. Capel from the University of United Kingdom have published the research work: Hydroxychloroquine reduces heart rate by modulating the hyperpolarization-activated current If_ Novel electrophysiological insights and therapeutic potential, in the Journal: (JOURNAL) of 10,/Oct/2015
- what: The aim of this study was to investigate the propensity of hydroxychloroquine (HCQ) to cause bradycardia. The experiments described herein studying the funny current closely mirror those first performed to investigate the effects of known If blockers (eg, ZD7288, ivabradine), and suggest that further studies regarding cardiac modulation by HCQ is warranted. s*Disclosure . . .
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