Vascular endothelial growth factor augments the tolerance towards cerebral stroke by enhancing neurovascular repair mechanism

HIGHLIGHTS

  • who: Adnan Ghori from the Department of Neurosurgery, Universitätsmedizin Charité, Berlin, Germany have published the Article: Vascular Endothelial Growth Factor Augments the Tolerance Towards Cerebral Stroke by Enhancing Neurovascular Repair Mechanism, in the Journal: (JOURNAL)
  • what: The authors report that the transgenic overexpression of VEGF (GOF) prior to the stroke stabilizes the vasculature and prevents blood-brain barrier disruption in young and aged animals after stroke. Subsequently, the authors aimed to understand the mechanistic pathways triggered by VEGF-GOF when stabilizing the vasculature following ischemia. With these studies, the authors demonstrate two beneficial effects . . .

     

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