Early activation of the cardiac cx3cl1/cx3cr1 axis delays β-adrenergic-induced heart failure

HIGHLIGHTS

  • who: M. Flamant from the Institut have published the research work: Early activation of the cardiac CX3CL1/CX3CR1 axis delays β-adrenergic-induced heart failure, in the Journal: Scientific Reports Scientific Reports
  • what: The project was submitted to the French Ethic Committee CEEA (Comité d'Ethique en Expérimentation Animale) and obtained the authorization Ce5/2012/050 and APAFIS#1729-2015083114195840v8. Based on systematic echocardiographic analyses, the study provides a detailed characterization of iso-induced ECH myeloid cells using a combination of flow cytometry, tissue immunostaining, transcriptomic and secretomic approaches. Mechanistically, the authors show the synergistic . . .

     

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