Expression and mechanism of spleen tyrosine kinase activation by angiotensin ii and its implication in protein synthesis in rat vascular smooth muscle cells*

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• who: Fariborz A. Yaghini from the Fariborz AYaghini1, Fang Li, and Kafait U. Malik, From the Department of Pharmacology and Centers of Vascular Biology and Connective Tissue Diseases, College of Medicine, University of Tennessee Health Science Center, Memphis, Tennessee , Syk, a, kDa tyrosine kinase, is involved in development, differentiation, and signal transduction of hematopoietic and some non-hematopoietic cells. This study determined if Syk is expressed in vascular smooth muscle cells (VSMC) and contributes to angiotensin II (Ang II) signaling and protein synthesis. Syk was found in VSMC and was phosphorylated by Ang II through , receptor. Ang . . .
  

   

  

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