Development of a modular vaccine platform for multimeric antigen display using an orthobunyavirus model

HIGHLIGHTS

  • who: Andrea Aebischer and colleagues from the Laboratory of Virology, Wageningen Bioveterinary Research, RA Lelystad, The Netherlands have published the research work: Development of a Modular Vaccine Platform for Multimeric Antigen Display Using an Orthobunyavirus Model, in the Journal: Vaccines 2021, 651 of /2021/
  • what: The authors developed a modular vaccine platform for multivalent antigen display using lumazine synthase (LS) from the hyperthermophilic bacterium Aquifex aeolicus as a scaffold-protein (also designated as "multimeric protein scaffold particle" or "MPSP"). The authors directly compared two of these methods with regards to efficiency and potency. The authors . . .

     

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