Increased levels of the synaptic proteins psd-95, snap-25, and neurogranin in the cerebrospinal fluid of patients with alzheimer’s disease

HIGHLIGHTS

• who: Pia Kivisäkk from the Department of Neurology, Alzheimer's Clinical and Translational, Charlestown, MA, USA have published the research: Increased levels of the synaptic proteins PSD-95, SNAP-25, and neurogranin in the cerebrospinal fluid of patients with Alzheimer’s disease, in the Journal: (JOURNAL)
• what: The novel Simoa assays used in this study showed excellent performance in measuring CSF levels of PSD-95 and SNAP-25.
• how: The results showed that subjects with AD on average had markedly increased PSD-95 and SNAP-25 CSF levels compared to both healthy . . .
  

   

  

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