Inhibiting sphingosine 1-phosphate receptor subtype 3 attenuates brain damage during ischemia-reperfusion injury by regulating nnos/no and oxidative stress

HIGHLIGHTS

  • who: Guozhong Li and Di Zhong from the Department of Neurology, The First Affiliated Hospital of Harbin Medical University, Harbin, China have published the research work: Inhibiting Sphingosine 1-Phosphate Receptor Subtype 3 Attenuates Brain Damage During Ischemia-Reperfusion Injury by Regulating nNOS/NO and Oxidative Stress, in the Journal: (JOURNAL)
  • how: The results showed that 24 h after tMCAO there was more fluorescent staining of nNOS in the peri-ischemic regions (p and amplt 0.01).
  • future: It is necessary to use gene knockout in future research. More research is needed to . . .

     

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