Upregulated lncarat in schwann cells promotes axonal regeneration by recruiting and activating proregenerative macrophages

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  • who: Gang Yin from the All experimental animal protocols were approved by the Ethics Committee of the Shanghai General Hospital, Shanghai JiaoTong University School of MedicineAdult male Sprague-Dawley rats (180, g) were obtained from the Zhejiang Chinese Medical University Laboratory Animal Research Center (Zhejiang, China) and maintained in, h light/12-h dark conditions with ad libitum access to food and water. Every effort was made to minimize the number of animals used and their suffering. The rat model of sciatic nerve crush injury was established according to a previous description (DadonNachum et_al, ). In brief, rats . . .

     

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