HIGHLIGHTS
- who: Hiba Hasan from the InstitutLiebig University Giessen, Germany have published the research: Mechanism of Inflammatory Associated Impairment of Sperm Function, Spermatogenesis and Steroidogenesis, in the Journal: (JOURNAL) of 28/04/2022
- how: Similar observations were made in_vivo where TNF-a deficiency prevented the MuV induced disruption in the BTB and loss in spermatids .
SUMMARY
The testis is an immune privileged organ that tolerates the introduction of sperm autoantigens at the onset of puberty without eliciting an inflammatory immune_response. The testis in mammals evolved multiple strategies to preserve this immunocompromised status . . .
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