Adeno-associated viral vectors as versatile tools for neurological disorders: focus on delivery routes and therapeutic perspectives

HIGHLIGHTS

• who: Ana Fajardo-Serrano and colleagues from the Centro de Investigación Médica Aplicada (CIMA), Department of Neuroscience, Universidad de Navarra, Madrid, Spain have published the article: Adeno-Associated Viral Vectors as Versatile Tools for Neurological Disorders: Focus on Delivery Routes and Therapeutic Perspectives, in the Journal: Biomedicines 2022, 10, 746. of /2022/

SUMMARY

Adeno-associated viral_vectors (AAVs) are members of Dependoparvovirus in the Parvoviridae family. Rep-independent recombinant AAVs are used for gene therapy purposes, to avoid the preference of integration of Rep proteins into the AAVS1 site inside of Ch19 . . .

 



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