Global deletion of aldh1a1 and aldh1a2 genes does not affect viability but blocks spermatogenesis

HIGHLIGHTS

  • who: Traci Topping from the School of Molecular Biosciences, College of Veterinary Medicine, Washington State University, Pullman, WA, United States have published the research: Global Deletion of ALDH1A1 and ALDH1A2 Genes Does Not Affect Viability but Blocks Spermatogenesis, in the Journal: (JOURNAL)
  • what: One of the goals of this study was to examine the viability of mice after global deletion of 2 of the 3 Aldh1a genes and a decreased ability to synthesize RA.
  • how: Their data showed that the deletion of all 3 Aldh1a genes in Sertoli cells blocked spermatogenesis at the . . .

     

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