Molecular studies on the voltage dependence of dihydropyridine action on l-type ca2+ channels

HIGHLIGHTS

• who: Ilona Bodi from the (UNIVERSITY) have published the article: Molecular Studies on the Voltage Dependence of Dihydropyridine Action on L-type Ca2+ Channels, in the Journal: (JOURNAL) of July/17,/1997
• what: The authors investigated the voltage-dependent action of DHPs with mutants of the IIIS6 and IVS6 segments of a cardiac calcium channel.
• how: Several point mutations (Y1178A I1182A I1182F and Y1489I) in IIIS6 and IVS6 transmembrane segments of the cardiac calcium channel were tested for their involvement in of the antagonist and they raised the possibility that this phenomenon is . . .
  

   

  

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