Hiv-1 vpr protein induces proteasomal degradation of chromatin-associated class i hdacs to overcome latent infection of macrophages*

HIGHLIGHTS

  • who: Bizhan Romani from the (UNIVERSITY) have published the research work: HIV-1 Vpr Protein Induces Proteasomal Degradation of Chromatin-associated Class I HDACs to Overcome Latent Infection of Macrophages*, in the Journal: (JOURNAL) of August/30,/2015
  • what: The authors report novel protein targets for Vpr that explain the previously described functions of this protein. The authors showed that JOURNAL OF BIOLOGICAL CHEMISTRY 2708 JOURNAL OF BIOLOGICAL CHEMISTRY VOLUME 291.
  • how: The results indicated that depletion of class I HDACs was more drastic on chromatin as the chromatin associated class I HDACs . . .

     

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