Impact of bone marrow atp-binding cassette transporter a1 deficiency on atherogenesis is independent of the presence of the low-density lipoprotein receptor

HIGHLIGHTS

• who: Amber B. Ouweneel from the Division of BioTherapeutics, Leiden Academic Center for Drug Research, Leiden University, Einsteinweg, CC, Leiden, the Netherlands have published the paper: Impact of bone marrow ATP-binding cassette transporter A1 deficiency on atherogenesis is independent of the presence of the low-density lipoprotein receptor, in the Journal: (JOURNAL)
• what: Besides the primary aim to elucidate the influence of Ldlr on the atheroprotective function of hematopoietic Abca1, the study set up also allowed the authors to investigate the basic role of macrophage Ldlr in foam cell formation and atherosclerosis.
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