Structural determinants of binding the seven-transmembrane domain of the glucagon-like peptide-1 receptor (glp-1r)*

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  • who: Dehua Yang from the (UNIVERSITY) have published the research work: Structural Determinants of Binding the Seven-transmembrane Domain of the Glucagon-like Peptide-1 Receptor (GLP-1R)*, in the Journal: (JOURNAL) of June/17,/2016
  • what: The aims of this study were therefore to identify the structural determinants of GLP-1 binding in the 7TM domain of GLP-1R and to elucidate the molecular mechanism of selective recognition of GLP-1. The R1902.60bA, R1902.60bK, K1972.67bA, D1982.68bA, K2884.64bA, E292ECL2A, and W297ECL2A GLP-1R mutations analyzed in this study showed similar . . .

     

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