The atpase srcap is associated with the mitotic apparatus, uncovering novel molecular aspects of floating-harbor syndrome

HIGHLIGHTS

  • who: Giovanni Messina from the Università Roma, Via dei Sardi, Roma, Italy have published the research work: The ATPase SRCAP is associated with the mitotic apparatus, uncovering novel molecular aspects of Floating-Harbor syndrome, in the Journal: (JOURNAL)
  • what: The authors focused on Cit-K, MKLP2, Aurora B, INCENP, MKLP1, PLK1, CEP55, Anillin, Alix, and Spastin, ten well-known proteins that localize to the midbody and are required for cytokinesis . The authors propose that mitosis and cytokinesis failure may contribute to the onset of developmental defects characteristic of FHS.
  • how: Antibodies Primary antibodies . . .

     

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