HIGHLIGHTS
- who: Peter Tompa from the (UNIVERSITY) have published the Article: On the Sequential Determinants of Calpain Cleavage*, in the Journal: (JOURNAL) of December/18,/2003
- how: To advance the understanding of what constitutes a calpain site the authors carried out a systematic analysis of these data and constructed a preference matrix. This feature is demonstrated by inhibitory mutations in the autolysis sites of Drosophila calpain B. Fig 3 shows that mutations hamper autolytic cleavage of the given site amino_acids were replaced on either one or both sides of the two major autolytic sites with amino_acids . . .
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