Conserved cysteine and tryptophan residues of the endothelin-converting enzyme-1 cxaw motif are critical for protein maturation and enzyme activity*

HIGHLIGHTS

• who: Kathryn J. MacLeod from the (UNIVERSITY) have published the paper: Conserved Cysteine and Tryptophan Residues of the Endothelin-converting Enzyme-1 CXAW Motif Are Critical for Protein Maturation and Enzyme Activity*, in the Journal: (JOURNAL)
• how: These results indicated that ECE-1a cannot be metabolically labeled in_vivo by a mevalonolactone derivative.
• future: Kinetic work using purified enzyme will be needed to better characterize the function of the tryptophan residue on enzyme activity.

SUMMARY

Received for publication, May 2, 2001 May, and in revised form, June 4, 2001 June . . .

 



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