Inactivation of endothelial adam17 reduces retinal ischemia-reperfusion induced neuronal and vascular damage

HIGHLIGHTS

  • who: Diana R Gutsaeva and collaborators from the Department of Ophthalmology, Medical College of Georgia, Augusta University, Augusta, GA, USA have published the article: Inactivation of Endothelial ADAM17 Reduces Retinal Ischemia-Reperfusion Induced Neuronal and Vascular Damage, in the Journal: (JOURNAL) of February/22,/2018
  • what: The analysis showed an increase in leukocyte adhesion in ischemia-injured retinal microvasculature of control ADAM17flox mice (p and amp;lt; 0.001 compared to corresponding sham; Figure 7A,B).
  • how: The authors used conditional knockout mice that lack expression of ADAM17 in endothelial cells. The data . . .

     

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