Role of exo1 nuclease activity in genome maintenance, the immune response and tumor suppression in exo1 mice

HIGHLIGHTS

• who: Shanzhi Wang et al. from the Department of Cell Biology, Albert Einstein College of Medicine, Morris Park NY, USA, position: Department of Chemistry, University of Arkansas at Little Rock, Little Rock, AR, USA have published the article: Role of EXO1 nuclease activity in genome maintenance, the immune response and tumor suppression in Exo1 mice, in the Journal: (JOURNAL)
• what: The authors show that Exo1DA/DA and Exo1- /- mice are compromised in canonical DNA repair processing suggesting that the EXO1 enzymatic role is important for error-free DNA mismatch and double-strand break repair pathways . . .
  

   

  

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