Prostaglandin synthase-1 and prostaglandin synthase-2 are coupled to distinct phospholipases for the generation of prostaglandin d2 in activated mast cells*

HIGHLIGHTS

  • who: Srinivasa T. Reddy from the (UNIVERSITY) have published the paper: Prostaglandin Synthase-1 and Prostaglandin Synthase-2 Are Coupled to Distinct Phospholipases for the Generation of Prostaglandin D2 in Activated Mast Cells*, in the Journal: (JOURNAL) of October/17,/1996
  • what: In this report the authors investigate the roles of sPLA2 and cPLA2 in early, PGS1-dependent PGD2 synthesis and late, PGS2-dependent PGD2 synthesis following mast cell activation by aggregation of high affinity IgE receptors.
  • how: To demonstrate that the late burst of PGD2 synthesis occur- ring in the presence of . . .

     

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