Lcs-1 inhibition of superoxide dismutase 1 induces ros-dependent death of glioma cells and degradates parp and brca1

HIGHLIGHTS

  • who: Min Ling from the Lanzhou University, China have published the research work: LCS-1 inhibition of superoxide dismutase 1 induces ROS-dependent death of glioma cells and degradates PARP and BRCA1, in the Journal: (JOURNAL)
  • what: To further test the activity of ROS induced by LCS-1, qRT-PCR was used to measure the expression of the targeting genes regulated by ROS pathways.
  • how: All experiments were performed at least three times and the representative results were shown. The results showed that SOD1 IHC scores were 224 ± 57 294 ± 51 238 ± 85 . . .

     

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