Identification of essential gata and ets binding motifs within the promoter of the platelet glycoprotein ibî± gene (∗)

HIGHLIGHTS

  • who: Yoshimi Hashimoto from the (UNIVERSITY) have published the Article: Identification of Essential GATA and Ets Binding Motifs within the Promoter of the Platelet Glycoprotein Ibα Gene (∗), in the Journal: (JOURNAL) of May/23,/1995
  • what: This experiment provided direct evidence that the GATA motif is required for full promoter activity, but also suggested that additional motifs can still support promoter activity even in the absence of a fully functional GATA.

SUMMARY

    Gel shift assays and site-directed_mutagenesis studies defined essential GATA and Ets binding motifs 93 and 150 nucleotides upstream . . .

     

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