Blood-brain barrier damage induces release of α2-macroglobulin*

HIGHLIGHTS

  • who: Luca Cucullo from the Departments have published the research work: Blood-Brain Barrier Damage Induces Release of α2-Macroglobulin*, in the Journal: (JOURNAL) of November/26,/2002
  • what: The authors focused on the role of astrocytes (AS) and endothelial cells (EC) in BBB maintenance by studying in_vitro cell culture and serum samples obtained from patients who underwent BBBD procedures during chemotherapy treatment.
  • future: The main finding from this work is that the antiproteolytic molecule ␣2M is increased in serum under conditions of blood-brain barrier failure.

SUMMARY

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