HIGHLIGHTS
- who: Benoit Schneider from the (UNIVERSITY) have published the Article: Pre-steady State of Reaction of Nucleoside Diphosphate Kinase with Anti-HIV Nucleotides*, in the Journal: (JOURNAL) of September/29,/1997
- what: The authors present pre-steady-state kinetic experiments to investigate the phosphorylation of the enzyme by antiviral ddNTPs.
SUMMARY
The fluorescence signal, which is correlated with the phosphorylation state of the catalytic histidine in the enzyme active_site, decreases upon ddNTP addition according to a monoexponential time course. The equilibrium dissociation_constants for ADP, GDP, ddADP, and ddGDP were also determined . . .
If you want to have access to all the content you need to log in!
Thanks :)
If you don't have an account, you can create one here.