Heparin binding induces a conformational change in pigment epithelium-derived factor*

HIGHLIGHTS

  • who: Zuzana Valnickova from the (UNIVERSITY) have published the research work: Heparin Binding Induces a Conformational Change in Pigment Epithelium-derived Factor*, in the Journal: (JOURNAL)
  • what: The authors have employed biochemical and biophysical methods to investigate this hypothesis.
  • how: This result is consistent with an increased segmental mobility or a local unfolding in that region upon heparin binding.

SUMMARY

    PEDF is present in several ocular compartments including the retinal and ciliary epithelia, the cornea, and the vitreous fluid. PEDF is found in a range of other tissues including . . .

     

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