HIGHLIGHTS
- who: Irene Palenca et al. from the Department of Physiology and Pharmacology "VErspamer", Sapienza University of Rome, Piazzale Aldo Moro, Rome, Italy have published the research work: N-Palmitoyl-D-Glucosamine Inhibits TLR-4/NLRP3 and Improves DNBS-Induced Colon Inflammation through a PPAR-Dependent Mechanism, in the Journal: Biomolecules 2022, 12, 1163. of 22/07/2022
- what: The authors demonstrated that micronized PGA significantly and dose-dependently reduces colitis severity improves intestinal mucosa integrity by increasing the tight junction proteins expression and downregulates the TLR-4/NLRP3/iNOS pathway via PPAR-α receptors signaling in . . .
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