HIGHLIGHTS
- who: Neha Sarodaya from the Graduate SchoolHanyang University have published the paper: Deubiquitinase USP19 extends the residual enzymatic activity of phenylalanine hydroxylase variants, in the Journal: Scientific Reports Scientific Reports
- what: Since the main objective of this study was to analyze the deubiquitinating effect of USP19 on PAH variants R241C and R243Q, the authors expanded the research on UPS-mediated degradation of PAH variants.
- how: The results showed that the interaction between USP19 and R243Q was weaker than that between USP19 and the R241C variant (Fig 3a).
SUMMARY
To . . .
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