Micro rna 148a induces apoptosis and prevents angiogenesis with bevacizumab in colon cancer through direct inhibition of rock1 / c- met via under hypoxia

HIGHLIGHTS

• who: ROCK et al. from the Division of Colorectal Surgery, Department of Surgery, Kaohsiung Medical University Hospital, Kaohsiung Medical University, Kaohsiung, Taiwan have published the article: Micro RNA 148a induces apoptosis and prevents angiogenesis with bevacizumab in colon cancer through direct inhibition of ROCK1 / c- Met via under hypoxia, in the Journal: (JOURNAL)
• what: This study examined the role of miR-148a in inhibiting VEGF and Mcl-1 secretion by directly targeting by downregulating HIF-1α under hypoxia. The research demonstrated that miR-148a downregulated HIF-1α/VEGF and Mcl-1 by directly targeting ROCK1 . . .
  

   

  

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